Cannabis And The “Runner’s High” Might Have More Similarities Than Previously Thought
What we know as “Runner’s High”, the euphoric feeling after running or vigorous exercise, is not triggered by endorphins, a type of opioid. Researchers from the University Medical Center in Hamburg, Germany found that running stimulates the body’s endocannabinoid system, the biological system that interacts with the cannabinoids like CBD and THC found in cannabis when used.
The researchers behind this study had a group of volunteers directed to run and walk at different speeds on a treadmill. The volunteers were given either naltrexone, a drug that is an opioid receptor blocker, or a placebo. The study found that…
“Opioid blockade did not prevent the development of euphoria and reduced anxiety as well as elevation of endocannabinoid levels following exercise. Moreover, the fraction of participants reporting a subjective runner’s high was comparable in the naltrexone and placebo-treated group.”
The study concluded that the development of a runner’s high does not depend on opioid signaling in humans, but makes endocannabinoid strong candidates in humans. This result replicates the outcome of a similar study done with mice.
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