Can Severe Anxiety Symptoms Be Alleviated With Full-Spectrum CBD? New Study Hopes To Shed Light.
At the recent Anxiety and Depression Association of America annual conference, a presentation suggested that using a cannabidiol sublingual product could alleviate severe anxiety and anxiety-related symptoms.
“This is the very first study looking at a whole plant, [high CBD], full-spectrum product in patients with moderate to severe anxiety,” Staci Gruber, PhD, director of Marijuana Investigations for Neuroscientific Discovery at McLean Hospital, said during the presentation.
Thus far, the researchers have completed the open-label phase of the study. The study aimed to evaluate clinical ratings of anxiety, mood, sleep, and quality of life in addition to understanding the product’s correct dose and assess cognitive performance on multiple measures. The study has about 14 patients, each of whom received 10 mg/ml of CBD over 4 weeks.
The drug in question was well-tolerated by the patients with none reporting any serious adverse events or intoxication. Analysis of the results showed that anxiety ratings improved significantly according to the Beck Anxiety Inventory (79.94% decrease), Overall Anxiety Severity and Impairment Scale (70.24% decrease), and the Hamilton Anxiety Rating Scale (82.98% decrease). Further, results showed a decrease of 77.93% on the Beck Depression Inventory and of 63.67% on the Profile of Mood States: Total Mood Disturbance. There were also significant improvements in ratings of sleep and quality of life. The next phase of the study, a double-blind, placebo-controlled phase, will help with putting together a definitive assessment.
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